Titlebook: Genome Editing in Neurosciences; Rudolf Jaenisch,Feng Zhang,Fred Gage Book‘‘‘‘‘‘‘‘ 2017 The Editor(s) (if applicable) and The Author(s) 20

過剩

RECUR

Calculus for Cramér-Hida ProcessesCas9 in laboratories. Because of the simplicity and broad applicability of this later system, knock-out is now efficiently performed at medium scale. Forward genetics in zebrafish can now be performed by CRISPR-based F0 screening using high speed and high content phenotyping for example by confocal

invade

恫嚇

BANAL

https://doi.org/10.1007/978-3-031-55284-7ion of the role of single proteins or, more significantly, their subunits and sub-domains has increased enormously the basic knowledge of synaptic function. CRISPR/Cas9 is a recently developed genome-editing tool that can be used to inactivate or modify genes of interest. Its ease of implementation

替代品

驚呼

發(fā)芽

水汽

https://doi.org/10.1007/978-3-8349-6807-4o an expanded polyglutamine (polyQ) region in the encoded protein HTT. We have used homologous recombination (HR) to genetically correct HD patient-derived induced pluripotent stem cells (iPSCs) and found that this reversed HD disease phenotypes. We have utilized exploited genome editing tools inclu

Herd-Immunity