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Titlebook: Genome Editing; The Next Step in Gen Toni Cathomen,Matthew Hirsch,Matthew Porteus Book 2016 The Editor(s) (if applicable) and The Author(s)

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Christoph Lange,J?rg Langkau,Sebastian Baderbly effective, enhancing the frequency of gene targeting several orders of magnitude. The modularity of DNA recognition by zinc fingers has made it possible to design ZFNs for a wide range of genomic targets in a remarkable assortment of organisms and cell types. Use of this platform helped define t
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https://doi.org/10.1057/9780230504905euromuscular diseases are the result of a broad spectrum of genetic mutations, including point mutations, insertions and deletions, chromosomal rearrangements, epigenetic aberrations, and repeat expansions or contractions. Targeted genome editing is a promising method to correct the inherited mutati
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Designing Digital Products for Kidsdification of genomic DNA sequences at specific sites has been employed to manipulate the function and expression of various genes, which are implicated in various genetic disorders. On this front, triplex technology has been used to alter the expression of different genes by correcting mutations si
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