Titlebook: Genetics Meets Metabolomics; from Experiment to S Karsten Suhre Book 2012 Springer Science+Business Media, LLC 2012 Metabolomics.Systems Bi

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Sinnvolle alternative Weiterbildung,returned. Much of the research for the past 30 years has focused entirely on molecular biology and, while some stunning discoveries have been made with regard to oncogenes, other aspects of cancer cells have largely gone unnoticed “as reported by McKnight (Science 330:1338–1339, 2010).” This renewed

ANIM

,Beendigung des Arbeitsverh?ltnisses,ond the complex traits behind diabetes and obesity (diabesity), a number of rare genetic disorders related to mitochondrial and peroxisomal function and metabolic myopathies directly affect fatty acid metabolism. The detailed molecular analysis of these disorders will provide deeper insight into the

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https://doi.org/10.1007/978-3-642-86112-3es. Quantitative Trait Locus mapping of metabolic phenotypes (mQTL) is a powerful approach to unravel the genetic component associated with metabolic profiles, and typically identifies genes associated with metabolic markers of disease. In this chapter we describe the various stages of the mQTL mapp

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CUMB

https://doi.org/10.1007/978-3-642-64953-0 conditions have been identified since the completion of the human genome by genome-wide association studies, it is still unclear for many of these genetic variants how they disrupt cellular processes. In this chapter we shall present the concept of genome-wide association studies with metabolomics.

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Introduction,odels. Then they address numerous human health related issues and finish with topics that require a systems approach. Chapters are chosen to be complimentary in their focus; some introduce a particular technology, others a new concept, and many a specific biological or biomedical application. In the

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