Titlebook: Genetic Models of Immune and Inflammatory Diseases; Abul K. Abbas,Richard A. Flavell Book 1996 Springer-Verlag New York, Inc. 1996 Antigen

characteristic

Globalanalyse des Diskursfeldes, is provided by antigen recognition, and is responsible for ensuring that the resultant immune response is specific for the eliciting antigen. For T lymphocytes, the second signal is provided by proteins, called co-stimulators, that are expressed on the surfaces of . (APCs). Only professional APCs,

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https://doi.org/10.1007/978-3-662-26482-9rs to be particularly important for CD8. cells, because soluble antigens usually do not enter the MHC class I pathway. Detailed knowledge of tolerance induction in peripheral T cells is essential for therapeutic intervention in autoimmune diseases, organ transplantation, or in attempts to break nonresponsiveness to tumor antigens.

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https://doi.org/10.1007/978-3-663-01691-5est of these disorders as well. A thorough elucidation of the basis for the association between B27 and disease would enhance our understanding of the roles that both genes and environmental agents play in producing chronic inflammatory diseases.

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Inflammatory Disease in HLA-B27 Transgenic Ratsest of these disorders as well. A thorough elucidation of the basis for the association between B27 and disease would enhance our understanding of the roles that both genes and environmental agents play in producing chronic inflammatory diseases.