| 書目名稱 | Genetic Models of Immune and Inflammatory Diseases | | 編輯 | Abul K. Abbas,Richard A. Flavell | | 視頻video | http://file.papertrans.cn/383/382556/382556.mp4 | | 叢書名稱 | Serono Symposia USA | | 圖書封面 |  | | 描述 | This book contains the proceedings of the Serono Symposia USA interna- tional symposium on Genetic Models of Immune and Inflammatory Dis- eases held on October 20 to 23, 1994, in Savannah, Georgia. The advent of methods for introducing genes into the germlines of mice, and for targeted disruption of particular genes by homologous recombination, has provided scientists in many disciplines with an extraordinarily powerful set of analyti- cal tools. Some of the most informative applications of transgenic and gene knockout technology have been in studies of lymphocyte development and activation. The goal of this symposium was to bring together investigators using these genetic approaches for analyzing the immune system, with a view to defining common themes and novel directions. Transgenic mice have a wide variety of important applications in immu- nology. Defined proteins can be expressed in selected tissues throughout development, thus acquiring the essential characteristic of "self" antigens. Such models have been used to study how immune responses to these artificially created "self" antigens are controlled. Antigen receptors of lym- phocytes have been expressed as transgenes, and | | 出版日期 | Book 1996 | | 關(guān)鍵詞 | Antigen; antigen presentation; autoimmunity; cytokine; cytokines; diseases; infection; infections; interfero | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4612-2376-4 | | isbn_softcover | 978-1-4612-7520-6 | | isbn_ebook | 978-1-4612-2376-4 | | copyright | Springer-Verlag New York, Inc. 1996 |
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