Titlebook: Genetic Engineering; Principles and Metho Jane K. Setlow,Alexander Hollaender Book 1984 Springer Science+Business Media New York 1984 genet

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Vectors for Expressing Open Reading Frame DNA in , Using , Gene Fusions,eterologous gene expression, bacterial initiation signals for transcription and translation must be spliced to the foreign coding sequence to create gene fusions. To produce a complete protein, the fusion joint must be at the start of the foreign gene. This requires precise splicing and can involve

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Rearrangement and Activation of C-MYC Oncogene by Chromosome Translocation in B Cell Neoplasias,t of band deletions, reciprocal translocations and in some cases trisomy of a specific chromosome (1–3). Until recently, the molecular basis of these chromosomal rearrangements and the significance of their association with specific malignancies remained unknown. Cellular oncogenes (almost invariabl

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Screening for and Characterizing Restriction Endonucleases,The type II restriction endonucleases are the enzymes which enable scientists to cleave DNA at specific sequences. In 1974, Richard Roberts distributed a list of 30 restriction endonucleases. Eighteen of these recognized unique sequences; the remainder were isoschizomers, enzymes from different bact

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Molecular Studies of Mouse Chromosome 17 and the T Complex,ular terms. While a direct assault on the molecular biology of man was clearly not feasible prior to the age of recombinant DNA, earlier studies of simpler organisms provided a wealth of information on basic molecular principles that operated in human beings as well. Nevertheless, less complex organ

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