Titlebook: Genetic Engineering; Principles and Metho Jane K. Setlow Book 2003 Kluwer Academic/Plenum Publishers 2003 DNA.Genotyp.Nucleotide.Promoter.b

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Development of Targeted Viral Vectors for Cardiovascular Gene Therapy,cquired and inherited nature has driven an explosion of published work in the field of gene therapy. Gene therapy has enormous potential to provide new treatments that strike directly at the heart of molecular defects to produce the next generation of molecular medicines in diseases for which curren

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Practical Applications of Rolling Circle Amplification of DNA Templates, time, a number of in vitro applications of the rolling circle mechanism have been described (.). The three basic in vitro forms of rolling circle amplification (RCA) can be distinguished by thenumber of primers used in a reaction (see Figure 1). In the linear form of RCA, a DNA circle is amplified

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Bacterial Ion Channels, role played by the membrane in energy transduction. The presence of channels in the outer membrane of Gram negative bacteria was known and the physiological roles, structures and genetics were already well-established (.). A number of studies subsequently demonstrated pressure-sensitive channels in

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,Targeted Mutagenesis in Yeast with Oligonucleotides,organization have been greatly increased. Gene targeting and site-directed mutagenesis have been instrumental in dissecting genetic pathways, studying gene regulation and analyzing protein structure-function relationships. Stable modifications of chromosomal DNA are preferable to the addition of uns

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