Titlebook: Genetic Approaches in the Prevention of Mental Disorders; Proceedings of the j Victor Bulyzhenkov,Yves Christen,Leonid Prilipko ( Conferenc

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Victor Bulyzhenkov,Yves Christen,Leonid Prilipko (

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Genetic Epidemiology Strategies in Psychiatric Diseases,e segregation of the disease in families is not sufficient to determine the way in which genetic susceptibility is transmitted. To study such diseases with a complex and most likely heterogeneous etiology, genetic epidemiology now focuses on new strategies using genetic markers which can be applied

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New Genetic Strategies in Neuropsychiatric Disorders, Table 1 summarizes concordance rates for manic-depression in twin studies of manic-depressive probands (Mendlewicz 1988). Concordance rates are consistently higher in monozygotic (MZ) than dizygotic pairs, but they do not reach the 100% value in MZ pairs, indicating that nongenetic (environmental)

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,Molecular Approaches Toward the Isolation of the Huntington’s Disease Gene,meric subband 4pl6.3, between the anonymous DNA marker D4S10 and the telomere. Physical mapping and cloning strategies have been used to complement genetic analysis in determining the location of the HD mutation. All available DNA markers within 4pl6.3 have been used to construct a long range restri

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