Titlebook: Genes and the Motivation to Use Substances; Scott F. Stoltenberg Book 2014 Springer Science+Business Media New York 2014 gene expression.g

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Local Communities and Global Resistancet while most of the research in addiction genetics is not explicitly focused on motivational constructs per se, the work increases knowledge of the biological pathways that influence risk for addiction, at least some of which involve aspects of substance use motivation. So, such work has the potenti

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https://doi.org/10.1007/978-1-349-63055-4ithin a developmental framework. That is, initiation of substance use in adolescence and escalation to substance abuse in early adulthood are strongly age-graded, with the relevant behavioral risk and protective factors manifesting early in development, often prior to substance use onset. In this ch

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https://doi.org/10.1057/9781137462237strated that cigarette smoking is associated with changes in the DNA methylation signature of peripheral blood cells. The changes associated with this type of substance use are both dose and time dependent. These changes in DNA methylation are also accompanied by changes in gene transcription and pr

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Mechthild von Vacano,Silke Schwarz to impulsivity and of ways the pathways and genes can also influence other behaviors in a pleiotropic fashion. The effects of rare and common variants of MAOA and HTR2B genes are dependent on context. These contexts include stress and endocrine exposures with genotype effect being dependent on the

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