Titlebook: Generalized Epilepsy; Neurobiological Appr Massimo Avoli,Pierre Gloor,Robert Naquet Book 1990 Birkh?user Boston, Inc. 1990 PET.brain.cortex

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Changes in Extracellular Ions Associated with Epileptiform Dischargespartments. Thus, it has been shown that intense neuronal activity is associated with changes in the concentration of extracellular potassium ([K.].), sodium ([Na.].), calcium ([Ca.].), magnesium ([Mg.].), and chloride ([Cl?].) ions and in pH (Benninger et al., 1980; ten Bruggencate et al., 1976; Die

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Excitant Amino Acids in Epilepsyptors) results in a neuronal firing pattern that is similar to the paroxysmal depolarizing shift reported in experimental and human focal epilepsy (Peet et al., 1987), and altered EAA receptors have been reported in human epileptic tissue (Geddes et al., 1987). Excitant amino acid antagonists block

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https://doi.org/10.1007/978-981-10-3069-7ed in the cortex. In this review of experimental findings obtained in both in vivo and in vitro brain preparations, we have set as our goal understanding the differences that might exist at the cellular level in these epileptic patterns in humans.

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Unanswered Clinical Questions in Generalized Epilepsy epilepsy present. Answers to these problems, many as yet unavailable, should permit not only better control of the symptoms but also rational correction of the causes, and, eventually, prevention of the occurrence of generalized epilepsy, this experiment of nature that is so closely related to the normal functioning of the brain.

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Focal and Generalized Epileptiform Activity in the Cortex: In Search of Differences in Synaptic Meched in the cortex. In this review of experimental findings obtained in both in vivo and in vitro brain preparations, we have set as our goal understanding the differences that might exist at the cellular level in these epileptic patterns in humans.

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978-1-4684-6769-7Birkh?user Boston, Inc. 1990