Titlebook: Gene- and Cell-Based Treatment Strategies for the Eye; Elizabeth P. Rakoczy Book 2015 Springer-Verlag Berlin Heidelberg 2015 Complex eye d

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Gene Therapy and Stem Cell Therapy: Overview, scientific discoveries that contributed, we have endeavored to crystallize the steps that were the most important and presented them in the context of scientific history. The birth of genetics led to the discovery of DNA, understanding of inheritance, variations, and mutations. However, not until t

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,Gene Therapy for Leber’s Congenital Amaurosis Due to , Mutations,’s congenital amaurosis (LCA) due to . mutations. In the past 7 years, eight different clinical trials have been carried out evaluating safety and efficacy of recombinant virus-mediated delivery of the normal copy of .. The studies have differed in a number of variables, including dose and volume of

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Gene Therapy for Choroideremia,h century. In sufferers, the appearance of the fundus is of a characteristic pale colour caused by the loss of the outer retina, retinal pigmented epithelium and choroidal vessels, leading to exposure of the underlying sclera. Visual symptoms begin with reduction of night vision and gradually progre

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