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Titlebook: Gene Transfer; Raju Kucherlapati Book 1986 Plenum Press, New York 1986 Chromosom.DNA.Embryo.cell lines.gene expression.gene therapy.gene t

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書目名稱Gene Transfer
編輯Raju Kucherlapati
視頻videohttp://file.papertrans.cn/382/381991/381991.mp4
圖書封面Titlebook: Gene Transfer;  Raju Kucherlapati Book 1986 Plenum Press, New York 1986 Chromosom.DNA.Embryo.cell lines.gene expression.gene therapy.gene t
描述Genetic analysis of microbial systems provided us with the foundation for un- derstanding gene structure, expression, and regulation. It was long felt that the ability to generate mutants and conduct genetic studies in mammalian systems would prove to be equally useful. However, genetic analysis based on sexual systems is difficult in mammals because of the long generation times and the inability to perform controlled matings. As a result, genetic analysis of mam- malian systems had to await the development of parasexual systems. This book is an attempt to bring together descriptions of a number of these parasexual systems. A common theme of all the parasexual systems is the transfer of genetic information from a defined source into a specific cell type. This volume deals with a number of methods of gene transfer into mammalian cells. The early methods of gene transfer involved transfer of relatively large amounts of genetic information. These include somatic cell hybridization, microcell fusion, and chromosome transfer, which constitute the first part of this book. Each of these methods has already proven to be of enormous value in arriving at a genetic understanding of the mammal
出版日期Book 1986
關(guān)鍵詞Chromosom; DNA; Embryo; cell lines; gene expression; gene therapy; gene transfer; genes; hybridization
版次1
doihttps://doi.org/10.1007/978-1-4684-5167-2
isbn_softcover978-1-4684-5169-6
isbn_ebook978-1-4684-5167-2
copyrightPlenum Press, New York 1986
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Vectors for Gene Transfer Derived from Animal DNA Viruses: Transient and Stable Expression of Transeach of the cited families of DNA viruses. Many recent experiments have used .-acting elements [e.g., simian virus 40 (SV40) 72-base-pair (bp) repeat or the herpes simplex type 1 thymidine kinase promoter] derived from viruses that affect transcription of linked genes in otherwise nonviral recombina
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Homologous Recombination in Mammalian Somatic Cells,zberg, 1981) microinjection into somatic cells (Anderson .., 1980; Capecchi, 1980) or into embryos (Gordon .., 1980). Understanding the structure of DNA and RNA viral genomes has permitted the construction of a variety of different vectors for introduction of genetic information into mammalian cells
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https://doi.org/10.1007/978-94-009-2093-4each of the cited families of DNA viruses. Many recent experiments have used .-acting elements [e.g., simian virus 40 (SV40) 72-base-pair (bp) repeat or the herpes simplex type 1 thymidine kinase promoter] derived from viruses that affect transcription of linked genes in otherwise nonviral recombina
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https://doi.org/10.1007/978-1-349-15508-8zberg, 1981) microinjection into somatic cells (Anderson .., 1980; Capecchi, 1980) or into embryos (Gordon .., 1980). Understanding the structure of DNA and RNA viral genomes has permitted the construction of a variety of different vectors for introduction of genetic information into mammalian cells
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