Titlebook: Gene Therapy in Reconstructive and Regenerative Surgery; Giorgio Giatsidis Book 2018 Springer International Publishing AG, part of Springe

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Gene Therapy in Tendon Repair and Regeneration,reds of thousands of people annually in the USA alone. Gene therapy for the purpose of tendon healing is used to manipulate the healing environment. In this chapter, we will define the issues with tendon injuries, the model of gene therapy, and the clinical problems that may be addressed with gene intervention.

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Immunoglobulin

Giorgio GiatsidisOffers a practical overview of the latest research discoveries and clinical trials in the field of gene therapy.Written by prominent surgeons.Also includes a chapter on how to develop gene therapy cli

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Principles of Gene Therapy in Reconstructive and Regenerative Surgery,d, genetically-modified keratinocyte sheets, to regenerate the entire epidermis of a pediatric patient affected by junctional epidermolysis bullosa [1]. The gene therapy-edited cells showed a sustained survival in vivo (>21?months), offering the possibility of a cure where other conventional therapi

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Gene Therapy in Pathologic Scars,n of collagens in the ECM, and altered regulation of growth factors/cytokines. Though their etiology still remains unclear and the postsurgical recurrence keeps a high profile, great efforts have been made on potential gene therapies for more specific, long-lived and hopefully cheaper results, thank

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Gene Therapy in Skeletal Muscle Repair and Regeneration,regeneration (SMR) and maintenance [1–6]. GT techniques are acquiring increasingly significant functions in approaching various surgical problems [7, 8]. A key insight necessary for maximizing the value from the great deal already known on the regulation of SMR is that every regulatory product is po