Titlebook: Gene Therapy for Autoimmune and Inflammatory Diseases; Yuti Chernajovsky,Paul D. Robbins Book 2010 Birkh?user Basel 2010 Arthritis.Autoimm

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Disease mechanisms, genetic susceptibility and therapeutic approaches in lupus disease,ent disease mechanisms. The complex nature of lupus immunopathology has provided a fertile field to investigate disease mechanisms and explore new approaches for therapy. However, it is also this complexity that is hampering efforts to identify therapies that benefit most patients. In this chapter,

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Development of AAV vectors for the therapy of autoimmune and inflammatory diseases,, and muscle disorders. In these cases, the AAV vector has demonstrated both safety and efficacy; therapeutic transgene expression was observed in humans for greater than 5 years without associated side effects. Within the past decade, great progress has been achieved in AAV vector optimization for