Titlebook: GTPase Protocols; The Ras Superfamily Ed Manser,Thomas Leung Book 2002 Humana Press 2002

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Pierre J. Magistretti,Fran?ois Ansermetne (proto-oncogene) encoding a Tyr kinase called c-Src in early 1980s, it was firmly established that the malignant transformation of normal cells is caused by a combination of the following genetic events: overexpression of a protooncogene or constitutive activation of its gene product (mitogenic s

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*Non-Euclidean (Hyperbolic) Geometry, of cytoskeletal structures, adhesion, motility, transcriptional activation, and cell-cycle progression (.–.). The Rho-like GTPases comprise a subfamily of the Ras superfamily of small guanosine triphosphate (GTP)-binding proteins. Like all members of the Ras superfamily, the Rho-GTPases function as