Titlebook: GLUCAGON: Its Role in Physiology and Clinical Medicine; Its Role in Physiolo Piero P. Foà,Jasbir S. Bajaj,Naomi L. Foà Conference proceedin

Morbid

Quantification of Plasma Glucagon Immunoreactive Components in Normal and Hyperglucagonemic States glucagon-specific” antiserum (30K). These fractions have approximate molecular weights of 2000, 3500, 9000 and 160,000 and respond differently to stimulation with arginine and suppression with glucose. The 3500 and 9000 m. w. fractions account for most of the rise in plasma glucagon observed in chr

Cirrhosis

Circulating Glucagon Components: Significance in Health and Diseasens is largely unknown, their relative abundance may vary under different physiologic and pathologic conditions. This paper describes the pattern of IRG components in normal subjects and in patients with renal failure, diabetes mellitus, glucagonoma and other conditions. The role of the kidneys and o

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Plasma Immunoreactive Glucagon in Depancreatized Animalsive material (gut GLI: calculated as the difference between total GLI measured with a crossreacting antiglucagon serum and GI) were elevated in the systemic blood of depancreatized dogs and rats. Glucose stimulated gut GLI secretion more effectively when introduced into the ileum than when introduce

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Heterogeneity of Gut Glucagon-Like Immunoreactivity (GLI)in the full homologous glucagon sequence and are immunologically related to the glucagon precursors found in pancreatic A cells. The essential difference between the gastrointestinal cells which produce GLIs and the pancreatic A cells is the degree to which these cells shorten a common primary gene

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Role of the Submaxillary Gland and of the Kidney in the Hyperglucagonemia of Eviscerated Ratse findings and the hyperglucagonemia previously observed in depancreatized and in eviscerated animals, prompted us to look for glucagon sources other than the pancreas and the gastrointestinal tract. Significant amounts of immunoreactive glucagon (IRG) were extracted from rat submaxillary and paroti

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The Versatile Role of Calcium in Glucagon Releasea multiple role in the secretory activity of the pancreatic A cell. First, a cellular accumulation of calcium may mediate the glucagonotropic action of arginine and of a mixture of pyruvate, fumarate and glutamate. Second, the presence of a sufficient amount of extracellular calcium seems to be a pr

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