Titlebook: GABAB Receptor; Giancarlo Colombo Book 20161st edition Springer International Publishing Switzerland 2016 GABA B receptor.Gastroesophageal

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Die Ewige Wiederkehr des Gleichen,ate (GHB)]. A number of studies have provided evidence that the behavioral effects of baclofen and GHB are mediated predominantly by GABA. receptors; however, there is growing evidence that the mechanisms mediating the effects of these two drugs are not identical. The differences between baclofen an

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Rezeption, Funktion und Aussagewert,ns why GABAergic compounds, especially orthosteric receptor agonists, display limited clinical efficacy as analgesics. Among these are the variations in GABA receptor expression and function that occur with the persistent receptor activation associated with a painful stimulus and the chronic adminis

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Chemistry of GABAB Receptor Ligands: Focus on Agonists and Antagoniststo develop GABAB receptor ligands for therapeutic application in a variety of diseases associated with dysfunctions of the gabaergic system. Although baclofen (Lioresal) is still the only approved GABA. receptor agonist, this sustained research effort has produced many new compounds which are able t