Titlebook: G Protein-Coupled Receptor Kinases; Vsevolod V. Gurevich,Eugenia V. Gurevich,John J.G. Book 2016 Springer Science+Business Media New York

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“Barcode” and Differential Effects of GPCR Phosphorylation by Different GRKsphorylation (the “barcode”) result in distinct consequences in receptor function and signaling. Here, we review these recent findings and discuss the ramifications of this phenomenon in biology and medicine.

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Rainer-Peter Meyer,Fabrizio Moro,Fritz Hefti receptor kinase 1 (GRK1), and a close homolog GRK7, are indispensable for timely phototransduction recovery and dark adaptation of retinal rod and cone photoreceptors. By phosphorylating activated visual pigments, these GRKs enable the binding of visual arrestins to photoexcited pigments to stop ph

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