Titlebook: G Protein-Coupled Receptor Genetics; Research and Methods Craig W. Stevens Book 2014 Springer Science+Business Media New York 2014 G Protei

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Importance of G Protein-Coupled Receptor Genetics in Clinical Medicineular regulatory activities. By virtue of widespread distribution and important roles in cell physiology and biochemistry, GPCRs play multiple important roles in clinical medicine. The understanding of how GPCRs interact with G proteins, effectors, as well as other regulatory proteins has enormous im

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Discovery and Function of the Very Large G Protein-Coupled Receptormpairment. VLGR1 is one of the few adhesion GPCR family members in which mutations have been shown to be responsible for a human malady. Mutations in VLGR1 in humans result in one form (2C) of Usher syndrome, the most common genetic cause of combined blindness and deafness. Consistent with this phen

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