Titlebook: eQTL Analysis; Methods and Protocol Xinghua Mindy Shi Book 2020 Springer Science+Business Media, LLC, part of Springer Nature 2020 mining.g

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https://doi.org/10.1007/978-3-319-27886-5detected as trait-associated in a population-based genome-wide association study (GWAS). Our method’s key step is to combine, within a na?ve Bayes-like framework, three quantities for each SNP: (1) the .-value for the association test between the SNP’s genotype and the trait; (2) the .-value for the

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Carsten Nieder,Luka Milas,K. Kian Angarch interest. Traditional eQTL methods focus on testing the associations between individual single-nucleotide polymorphisms (SNPs) and gene expression traits. A major drawback of this approach is that it cannot model the joint effect of a set of SNPs on a set of genes, which may correspond to biolo

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