Titlebook: Exploring Pancreatic Metabolism and Malignancy; Ganji Purnachandra Nagaraju,Aramati BM Reddy Book 2019 Springer Nature Singapore Pte Ltd.

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Role of Heat Shock Protein 90 in Diabetes and Pancreatic Cancer Management,ly coordinating regulatory mechanisms in order to control their activity. One of the key regulators responsible for the upregulation of Hsp90 is heat shock factor (HSF1), whose primary role is to bind heat shock elements (HSEs) with Hsp90 promoters. HSF1 functions by interacting with the transcripti

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Exosomes: Mediators and Therapeutic Targets of Diabetes and Pancreatic Cancer, mediators and therapeutic targets of diabetes mellitus and pancreatic cancer owing to their role in controlling .-cell mass and insulin signaling. Early diagnosis of diabetes and pancreatic cancer can remarkably expand therapeutic approaches and overall survival. Further, identification of biomarke

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Energy, Environment, and Sustainabilityated mitochondrial enzymes not only participate in the metabolic reprogramming of tumor cells but also modulate cellular processes involved in tumor proliferation and progression. In this review, we described the association between the deregulated mitochondrial enzymes and development of pancreatic cancer.

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https://doi.org/10.1007/978-3-642-36838-7rther understand the role this pathway can play in deadly diseases such as PC. In this chapter we will explore the role of the HIF-1α pathway in PC, and in metabolic disorders, such as diabetes mellitus, and studies that have been conducted in order to further holistically understand the role of HIF-1α.

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Book 2019et definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated w