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Titlebook: Extracellular ATP and adenosine as regulators of endothelial cell function; Implications for hea Evgenia Gerasimovskaya,Elzbieta Kaczmarek

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發(fā)表于 2025-3-21 16:41:57 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Extracellular ATP and adenosine as regulators of endothelial cell function
副標(biāo)題Implications for hea
編輯Evgenia Gerasimovskaya,Elzbieta Kaczmarek
視頻videohttp://file.papertrans.cn/320/319926/319926.mp4
概述The first book with a unique focus on the effects of extracellular nucleotides and adenosine in endothelial cells..Describes regulatory role of extracellular nucleotides and adenosine in angiogenesis,
圖書封面Titlebook: Extracellular ATP and adenosine as regulators of endothelial cell function; Implications for hea Evgenia Gerasimovskaya,Elzbieta Kaczmarek
描述.Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis. ..This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication. .This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and pathological conditions, i.e. pregnancy, hypoxia, hypertension, inflammation and diabetes. .In the book’s 12 chapters, the role of purinergic signaling in endothelium-dependent tissue perfusion, regulation of endothelial barrier function, and angiogenesis are discussed. The mechanisms of ATP release and its role in intercellular communication are also presented. .In addition, the book provides the most up to date mechanisms of extracellular nucleotide metabolism by purine-converting ecto-enzymes and their c
出版日期Book 2010
關(guān)鍵詞Activation; Extracellular ATP; Nucleotide; Purine; Pyrimidine; cells; endothelium; metabolism; regulation; ti
版次1
doihttps://doi.org/10.1007/978-90-481-3435-9
isbn_softcover978-94-007-9680-5
isbn_ebook978-90-481-3435-9
copyrightSpringer Science+Business Media B.V. 2010
The information of publication is updating

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發(fā)表于 2025-3-21 21:09:31 | 只看該作者
Nucleotides and Novel Signaling Pathways in Endothelial Cells: Possible Roles in Angiogenesis, Endowing nucleotide-mediated activation of focal adhesion kinase (FAK), AMP-activated protein kinase (AMPK) and endothelial nitric oxide synthase (eNOS), and document the role of Ca. in these pathways. Activation by extracellular nucleotides of mitogen-activated protein kinases (MAPK), such as extracell
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發(fā)表于 2025-3-22 05:53:12 | 只看該作者
The P2Y2 Nucleotide Receptor in Vascular Inflammation and Angiogenesis,gioplasty, and venous bypass graft failure. We have shown that activation of the P2Y. nucleotide receptor (P2Y.R) in vascular endothelial cells in vitro induces VCAM-1 (vascular cell adhesion molecule-1) expression and promotes the adherence of monocytes. VEGF, a pleiotropic factor that regulates en
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發(fā)表于 2025-3-22 12:38:18 | 只看該作者
Role of Purine-Converting Ecto-Enzymes in Angiogenic Phenotype of Pulmonary Artery Adventitial Vasally hypoxic calves. Because extracellular ATP and ADP are important regulators of vascular cell function, we hypothesized that these nucleotides may contribute to vasa vasorum neovascularization induced by chronic hypoxia. Treatment of pulmonary artery adventitial vasa vasorum endothelial cells (VVE
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發(fā)表于 2025-3-22 15:44:44 | 只看該作者
Stimulation of Wound Revascularization by Adenosine Receptor Activation,ved that topical application of a selective adenosine A. receptor agonist promotes wound healing in experimental animals, both healthy and with impaired healing. Histological analysis revealed that adenosine promoted granulation tissue formation, with increased cellularity, matrix deposition, and ve
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發(fā)表于 2025-3-22 22:08:58 | 只看該作者
Regulated Extracellular Nucleotide Metabolism and Function at the Mucosa,denosine (Ado) can regulate a number of processes at the mucosa, e.g. dampening of the inflammatory response and resultant tissue protection. Ado receptors are widely expressed on a variety of organs and cell types and have been demonstrated to be central to the modulation of inflammation. In many i
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