Titlebook: Excitotoxins; Proceedings of an In Kjell Fuxe,Peter Roberts,Robert Schwarcz Conference proceedings 1983 Springer Science+Business Media New

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https://doi.org/10.1007/978-3-663-07712-1 difficult to confirm its role as a neurotransmitter in the mammalian CNS. Unlike other putative neurotransmitters, glutamate fullfills a multitude of tasks in the brain. It is involved in energy metabolism and fatty acid synthesis, incorporated into proteins and peptides and is even a precursor for

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Springer Series in Optical Scienceslarize and excite neurones of the mammalian spinal cord (Curtis, .., 1959; 1960), and that similar excitatory effects could be elicited by a variety of other compounds chemically related to the natural substances (Curtis and Watkins, 1960; 1963). Curtis and Watkins (1960) set forth the criteria whic

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, and Forward Lease ,—Case Study,amate and aspartate from the tissue and decreased the synthesis of glutamine from a variety of radioactive precursors. These effects were attributed to alterations in glial cells secondary to massive depolarization of neurons. These results and those of others are discussed in terms of their implica

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