Titlebook: Evolutionary Tinkering in Gene Expression; Marianne Grunberg-Manago,Brian F. C. Clark,Hans G. Book 1989 The Editor(s) (if applicable) and

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The Evolutionary Origin of Glycosomes: How Glycolysis Moved from Cytosol to Organelle in Evolution,mes of substrates and should allow a faster rate of glycolysis than would be possible if substrates and enzymes were freely distributed over the entire cytosol. Indeed, trypanosomes have by far the highest rate of glycolysis in nature.

vertebrate

anaphylaxis

cular. Boehringer Mannheim has contributed since 1966. Furthermore. the Greek Ministry of Science and Culture has provided support at least for a social event during each ASI.978-1-4684-5666-0978-1-4684-5664-6

confederacy

Conformational Polymorphism in DNA,ried and include information transfer in which nucleic acids play a specialized role. The proteins form organized structures including the catalytically active molecules that are responsible for channelling the metabolic activity of the cell.

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Translational Control of Gene Expression in ,: The Case of Threonyl-tRNA Synthetase,ved in a large number of other functions, such as priming of roverse transcription (Kikuchi ., 1986), self splicing of the rRNA intron of the ciliate Tetrahymena and many other catalytic activities (Cech and Bass, 1986). This makes it likely that life began with RNA serving both as a genome and and

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Texture

Protein Engineering of Elongation Factor Tu,udy is the elongation factor EF-Tu. This was chosen because of its own fundamental biological importance, because of its recently-recognized significance as a member of a group of GTP-binding proteins of medical relevance, and finally because of existing experience and expertise with this protein in

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Translational Control by Phosphorylation of Mammalian Initiation Factors,f protein synthesized, called global control. Alternatively, the change may affect the synthesis of specific proteins, called mRNA-specific control. In either case, efficiency of translation is usually measured by radiolabeled amino acid incorporation into protein, or by the number and activity of r

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Ca2+-Calmodulin-Dependent Protein Kinases and Protein Kinase C: Functional Similarities, (Krebs, 1986). Two of the most intensively studied groups are Ca.-regulated, i.e. the Ca./calmodulin (CaM)-dependent and the Ca.-phospholipid (diacylglycerol)-dependent protein kinases. Of the enzymes belonging in the category of Ca./CaM-dependent kinases, myosin light chain kinases (MLCK) are dist

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