Titlebook: Evolutionary Systems Biology; Advances, Questions, Anton Crombach Book 2021Latest edition The Editor(s) (if applicable) and The Author(s),

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Experimental Investigations of the EHVE,ene network, and highlight novel insights into network evolution by compensatory developmental system drift. Finally, we discuss the prospect of simulating the phylogenesis of the gap gene network using in silico evolution. We conclude by arguing that our case study is a first step toward a more sys

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,Das Marketingverst?ndnis der Arbeit,out anatomical homology between the skeletal elements of fins and limbs. We will conclude by proposing that due to the counter-intuitive dynamics of gene regulatory feedback, integrative approaches that combine computer modeling, theory and experiments are essential to understand the evolution of mu

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Organisation der Externen Integration, building the phenotype during development (Waddington, Beyond reductionism, 1968). We argue that models including epigenetic factors exhibit features found in real GPMs that are not found in purely genetic models. Since these features are widely found in real GPMs, no model can be considered genera