| 書(shū)目名稱(chēng) | Evolution and Variation of Multigene Families | | 編輯 | Tomoko Ohta | | 視頻video | http://file.papertrans.cn/318/317681/317681.mp4 | | 叢書(shū)名稱(chēng) | Lecture Notes in Biomathematics | | 圖書(shū)封面 |  | | 描述 | During the last decade and a half, studies of evolution and variation have been revolutionized by the introduction of the methods and concepts of molecular genetics. We can now construct reliable phylogenetic trees, even when fossil records are missing, by compara- tive studies of protein or mRNA sequences. If, in addition, paleon- tological information is available, we can estimate the rate at which genes are substituted in the species in the course of evolution. Through the application of electrophoretic methods, it has become possible to study intraspecific variation in molecular terms. We now know that an immense genetic variability exists in a sexually repro- ducing species, and our human species is no exception. The mathematical theory of population genetics (particularly its stochastic aspects) in conjunction with these new developments led us to formulate the "neutral theory" of molecular evolution, pointing out that chance, in the form of random gene frequency drift, is playing a much more important role than previously supposed. I believe that the traditional paradigm of neo-Darwinism needs drastic revision. Also, the importance of gene duplication in evolution, as first | | 出版日期 | Book 1980 | | 關(guān)鍵詞 | Drosophila; Molekulargenetik; antibody; chromosome; evolution; gene; genetics; molecular genetics; populatio | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-93138-3 | | isbn_softcover | 978-3-540-09998-7 | | isbn_ebook | 978-3-642-93138-3Series ISSN 0341-633X Series E-ISSN 2196-9981 | | issn_series | 0341-633X | | copyright | Springer-Verlag Berlin Heidelberg 1980 |
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