Titlebook: Eukaryotic Cell Function and Growth; Regulation by Intrac Jacques E. Dumont,Barry L. Brown,Nicholas J. Marsh Book 1976 Springer Science+Bus

fibula

The Assay of Cyclic AMP in Biological Material,ntrations normally present in most cells and to the presence of other structurally similar compounds in much higher concentrations. With the advent over the last decade of numerous analytical procedures, the investigator is now faced with an almost bewildering choice of assay techniques. It is clear

震驚

BIPED

The Actions of Nucleotides on Adenylyl Cyclase Systems,osides. The original finding leading to this recognition (1, 2) was that under stringent assay conditions (using as substrate either low ATP or AMP-PNP) the liver plasma membrane adenylyl cyclase exhibited an almost total requirement for GTP (or ATP) to show activation by glucagon. Similar findings

Mettle

Cyclic AMP Metabolism of Some Fibroblastic and Epithelial Cells ,,sine 3′:5′-monophosphate (cyclic AMP) production. Cyclic AMP, in turn, interacts with the regulatory subunits of protein kinase, and also is degraded into 5’-AMP by cyclic nucleotide 3’:5’-phosphodiesterase (phosphodiesterase) (1). For these reasons it is common to use measurements of adenylate cycl

機(jī)警

Metabolism of Cyclic GMP in Vascular Smooth Muscle, Leukocytes, and Lung,clic AMP. Over the almost 20 years that cyclic AMP has been known, the methodology has been consistently improved and refined whereas experience in the extraction, purification and measurement of cyclic GMP from tissues is much less extensive. The radioimmunoassay of Steiner et al. (1) with its sens

Inelasticity

Cyclic Nucleotide Analogues,with the biological properties of cyclic AMP has increased rapidly. Then research groups at universities, research institutes and especially in the laboratories of the pharmaceutical industry began to modify cyclic AMP and other cyclic nucleotides systematically. More than 150 derivatives of cyclic

小木槌

Inexorable

The Actions of Nucleotides on Adenylyl Cyclase Systems,ems either positively or negatively. They appear to do so by affecting not only the degree of hormonal stimulation, but also the basal activity of the system and the receptor-hormone interaction. We shall review the experimental evidence relating to these effects and discuss the possibility that nuc

SEMI

為寵愛