Titlebook: Essentials of Radiofrequency Ablation of the Spine and Joints; Timothy R. Deer,Nomen Azeem Book 2021 The Editor(s) (if applicable) and The

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978-3-030-78034-0The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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Cosmopolitanism, Markets, and Consumptiono treat pain generators without the destructive effects associated with CRF. While the complete mechanism of action of PRF is not understood, the proposed mechanisms are the induction of long-term depression of synaptic potentials which modulate c-fiber transmission. This in turn decreases/inhibits

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