Titlebook: Essential Current Concepts in Stem Cell Biology; Beate Brand-Saberi Textbook 2020 Springer Nature Switzerland AG 2020 Adult Stem Cells.Epi

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Epigenetics of Somatic Cell Reprogramming,e) including histone methylation/acetylation, histone variants substitution, and DNA/RNA modification. In addition, we will discuss how these epigenetic modifications affect the production and quality of iPSCs, and thus obtain more efficient reprogramming methods.

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Dopaminergic Neuron-Related Stem Cells,econd most common neurodegenerative disease, Parkinson’s disease (PD). At present there are no cures for PD, and the main treatments currently available only temporarily offer symptom relief. A promising approach for disease-modifying treatment for PD is to transplant healthy mDA neurons into the pa

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Liver Disease Modelling,g and secreting numerous proteins that are necessary for a wide variety of functions. Many diseases affect the liver, impairing either selected functions or perturbing metabolism as a whole. Importantly, other organs, which depend on proteins secreted by the liver, are frequently co-affected. In ord

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Cord Blood Stem Cells,addition, cord blood has been under investigation in several clinical studies for neuronal disorders as cerebral palsy, stroke and autism. Cord-blood subpopulations as endothelial cells, mesenchymal stromal cells (CB MSC), unrestricted somatic stem cells (USSC) and cells derived from the cord (umbil