Titlebook: Ergot Alkaloids and Related Compounds; B. Berde,H. O. Schild (Emeritus Professor of Pharm Book 1978 Springer-Verlag Berlin · Heidelberg 19

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https://doi.org/10.1057/9780230389304ersally pressor (., 1906; . and ., 1907). The substance is considerably more potent than might appear from the experiments of early workers, who consistently used doses which must be regarded as toxic. A marked pressor effect can be obtained in the anesthetised cat with an intravenous dose as low as

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https://doi.org/10.1007/978-3-319-65115-6eflected in some of the names given to the early compounds extracted, e.g., chrysotoxin, secalintoxin (. and ., 1907). One such name persists even today: ergotoxine. The purpose of this chapter is to review the information available on the toxicity of chemically defined ergot derivatives, both in an

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978-3-642-66777-0Springer-Verlag Berlin · Heidelberg 1978

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