Titlebook: Epistasis; Methods and Protocol Jason H. Moore,Scott M. Williams Book 2015 Springer Science+Business Media New York 2015 Modern genetic ana

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Johan Huijsing,Rudy Plassche,Willy Sansenther tissue. In this chapter, two well-studied neuropsychiatric diseases are examined, Alzheimer’s disease (AD) and schizophrenia, which have been shown to have multiple and, often, replicated interactions that associate with clinical endpoints or related phenotypes. In each case, a single gene is r

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Domine M. W. Leenaerts,Peter W. H. de Vreederpretation of this variance partition is not trivial, especially concerning nonadditive components. In this chapter, we compile various uses of variance partitioning from published analyses, new simulations, and theoretical examples. We show ways in which advanced genetic modeling facilitates the an

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Martin Clara,Daniel Gruber,Wolfgang Klatzeror genes (quantitative trait loci or QTLs) to select individuals with superior performance and qualities. QTL or genetic effects, including epistatic effects, can be defined at the genotypic (functional) and gene (statistical) levels. In the past, the functional or statistical genetic effects have b

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