Titlebook: Epilepsy Towards the Next Decade; New Trends and Hopes Pasquale Striano Book 2015 Springer International Publishing Switzerland 2015 biolog

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https://doi.org/10.1007/978-94-010-9042-1epsy and headaches. During the latest decades, new data have emerged in favor of a non-random relationship between these two entities. They are both characterized by transient attacks of altered brain function with a clinical, pathophysiological, common genetic factors and therapeutic overlap, thus,

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https://doi.org/10.1007/978-1-4615-9630-1o present recurrent seizures. So, the challenge for new more efficacious and better tolerated drugs is continuing. Advances in understanding of pathophysiology of epilepsy and in the physiology of ion channels and other molecular targets provide opportunities to create new and improved AEDs. Potenti

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Prescription Drug and Pharmaceutical Policyargets (such as the vagus nerve). Stereotactic radiosurgery also provides a neuromodulatory approach, affecting the discharging behavior of epileptic neurons in absence of evident target necrosis. Cortical transections or Multiple Subpial Transections (MST) are a non-resective technique useful to tr

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https://doi.org/10.1007/978-3-322-91763-8ect in healthy tissues including the central nervous system and, as a direct consequence, the ability to deliver extremely high doses without induction of radionecrosis. Growing experimental evidence is showing remarkable tolerance of brain and spinal cord to irradiation with microbeam arrays delive

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Copy Number Variants and Epilepsy: New Emerging Syndromes,ntification of recurrent copy number variants (CNVs) associated with epilepsy. Among these a small number has been increasingly reported in association with a distinct epileptic phenotype, delineating emerging epileptic syndromes. To date, none of these CNVs underlying a specific epileptic condition

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