Titlebook: Epigenome-Wide Association Studies; Methods and Protocol Weihua Guan Book 2022 Springer Science+Business Media, LLC, part of Springer Natur

entice

A survey of knowledge-based systems,also show that eFORGE tissue-specific enrichment can be detected for sites below EWAS significance threshold. I develop on these and other analysis examples, extending our knowledge of eFORGE cell type- and tissue-specific enrichment results for different EWAS.

sperse

Cell Type-Specific Signal Analysis in Epigenome-Wide Association Studies,also show that eFORGE tissue-specific enrichment can be detected for sites below EWAS significance threshold. I develop on these and other analysis examples, extending our knowledge of eFORGE cell type- and tissue-specific enrichment results for different EWAS.

larder

VEN

Quantification Methods for Methylation Levels in Illumina Arrays,ch CpG site for a given sample, which include .-value, M-value, and N-value. The performance of three quantification methods of methylation levels has been examined with simulation study and 27K Illumina array data for obesity.

nitric-oxide

A Review of High-Dimensional Mediation Analyses in DNA Methylation Studies, mediation effects only involve selected (gene-specific) candidate methylation markers. There is an urgent need for appropriate analytical methods for EWAS mediation analysis. In this chapter, we provide an overview of recent advances on high-dimensional mediation analysis, with application to two DNA methylation data.

Awning

https://doi.org/10.1007/978-94-015-8812-6y combining information from individual studies and reduce the chances of false positives. This chapter introduces commonly used meta-analysis methods and analytical tools with application to EWAS data.

爆炸

The trace of the iterated resolvent kernel, testing. Compared to the traditional multiple testing procedure on a filtered CpG set, the proposed procedure circumvents the difficulty to determine the optimal ICC cutoff value and is overall more powerful. We illustrate the procedure and compare the power to classical multiple testing procedures using an example data.

贊美者

,Postemancipation Developments 1834–1865,s for BS-seq using the Bioconductor package DSS. The analysis scheme in this chapter will guide researchers through differential methylation analyses by providing step-by-step instructions for analytical tools.

RENIN

1064-3745 ation advice from the experts.This volume details features of DNA methylation data, data processing pipelines, quality control measures, data normalization, and to discussions of statistical methods for data analysis, control of confounding and batch effects, and identification of differentially met

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