Titlebook: Epigenetics, Brain and Behavior; Paolo Sassone Corsi,Yves Christen Book 2012 Springer-Verlag Berlin Heidelberg 2012 DNA methylation.Nucleo

Indent

https://doi.org/10.1007/978-3-662-05688-2rum of clinical heterogeneity might be due to the inter-individual difference in the capacity of “buffering” deleterious synaptic mutations. A better understanding of the interplay between genetic/epigenetic variations and synaptic homeostasis should shed new light on the causes of ASD and may provi

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ARC

Synaptic Epigenesis and the Evolution of Higher Brain Functions,

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Control of Neuronal Gene Transcription and Behavior by the Epigenetic Suppressor Complex G9a/GLP,s that is associated with the reduced expression of GLP/Ehmt1. In an attempt to unravel the mechanism of G9a/GLP regulated cognition and behavior, we will discuss the nature of gene expression changes associated with the loss of G9a/GLP.

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The Role of Histone Acetylation in Long-Term Memory Storage,Determining the genes regulated by histone acetylation after contextual learning will provide insight into the necessary components of memory consolidation and may lead to development of novel, selective therapeutics that enhance memory in diseases in which memory is affected.

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持久

Genetics and Epigenetics of Autism Spectrum Disorders,rum of clinical heterogeneity might be due to the inter-individual difference in the capacity of “buffering” deleterious synaptic mutations. A better understanding of the interplay between genetic/epigenetic variations and synaptic homeostasis should shed new light on the causes of ASD and may provi

prodrome

Analysis of MeCP2 Function in the CNS,like behavior and deficits in cue-dependent fear conditioning. We have also demonstrated that loss of MeCP2 in neurons results in a decrease in spontaneous excitatory synaptic transmission coupled with an increase in action potential-driven excitatory drive. The combined effort of behavioral and syn

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Jong Hyun Kim,Jung Min Han,Sunghoon Kimg to changes in gene expression that modulate neural and immune function. These studies define a biological basis for the interplay between environmental signals and the genome in the regulation of individual differences in behavior, cognition, and physiology.

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