Titlebook: Epigenetics in Cardiac Disease; Johannes Backs,Timothy A. McKinsey Book 2016 Springer International Publishing Switzerland 2016 Cardiac de

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Epigenetic Regulations in Cardiac Development,ction at very early development stages, whereas mild heart defects may trigger heart dysfunction until adulthood. The adult mammalian heart has very limited regenerative capacity. Designing therapeutic strategies for congenital heart disease is likely dependent on understanding the mechanisms of hea

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DNA Methylation in Heart Failure,ersial whether DNA methylation is functionally relevant for the initiation and progression of heart disease. This chapter explains the basic mechanisms and functional consequences of DNA methylation. Its potential role in heart disease and its link to other epigenetic processes are examined and summ

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