Titlebook: Epigenetics and Neuroendocrinology; Clinical Focus on Ps Dietmar Spengler,Elisabeth Binder Book 2016 Springer International Publishing Swit

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Intergenerational Effects of PTSD on Offspring Glucocorticoid Receptor Methylationies have prompted investigation into methylation of the . promoter, which regulates transcription of the glucocorticoid receptor gene. Here, we review evidence of . methylation alterations in offspring of parents exposed to extreme stress and offspring of parents who developed PTSD in response to ex

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Epigenetic Biomarkers for Early-Life Adversityment and increase the vulnerability to psychopathology epigenetic regulation. This chapter will review the findings from human studies that support this hypothesis. We will describe epigenetic changes associated with early-life adversity and will discuss their potential as biomarkers for early-life

Concomitant

Epigenetic Biomarkers of Prenatal Maternal Stresseen early social environment, epigenetics, and long-term outcomes. The implications of maternal care on DNA methylation as well as the importance of maternal well-being during pregnancy to prevent future health problems are considered.

Entirety

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Oxytocin Receptors and Neurobehavioring gene expression. Here, we provide an overview of the functional organization and epigenetic regulation of the murine and human oxytocin receptor gene..Studies in mice have shown that the oxytocin receptor gene (.) is epigenetically regulated by DNA methylation with experience- and tissue-specifi

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后退

Epialleles glucocorticoid receptor (GR) takes the central stage in balancing the activity of the HPA axis through its negative feedback on the peptides corticotrophin-releasing hormone and adrenocorticotropic hormone. The activity of GR, in turn, is also controlled by several cofactors including FK506-binding

recession

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STENT

Epigenetic Risk Factors for Diseases: A Transgenerational Perspectivevelopment and adulthood. While genetic features are embedded in the DNA sequence inherited from parents, non-genetic features (which include epigenetic modifications) are acquired through experiences and environmental exposure across life. However, it is now acknowledged that non-genetic features ca