Titlebook: Epigenetics - A Different Way of Looking at Genetics; Walter Doerfler,Petra B?hm Book 2016 Springer International Publishing Switzerland 2

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Matthias Staufenbiel,Paolo A. Paganetti)]. The current overview summarizes an update of the data presented at the Fifth Weissenburg Symposium 2014 (Weissenburg Symposia, .). In earlier studies on integrated adenovirus type 12 (Ad12) DNA in Ad12-transformed hamster cells, we discovered that the CpG methylation profiles in some of their ub

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https://doi.org/10.1007/978-3-540-37652-1ized and shown to have interesting antileukemic activity in 1964, have only recently been FDA and EMA approved for the treatment of myelodysplastic syndromes (MDS; 5-aza by FDA and EMA, decitabine by FDA) and acute myeloid leukemia (AML) of older patients unfit for intensive chemotherapy (EMA). Thes

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Noncoding RNAs and Chromatin Modifications in the Developmental Control of Imprinted Genes,domains, the ICR differentially structures higher-order chromatin that allows, or prevents, transcription of close-by genes. Here, I introduce the epigenetic phenomenon of genomic imprinting and discuss how long ncRNAs and chromatin contribute to its developmental regulation.

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Short Biologically Active Peptides as Epigenetic Modulators of Gene Activity,rious components of the cytoplasm and nucleus including DNA and RNA. In vitro peptides interact with various oligonucleotides and DNA; they can discriminate between methylated and unmethylated DNAs. Peptides investigated interact with histone H1 and core histones; this interaction depends on the his