Titlebook: Epidemiology of Human Congenital Malformations; Bengt K?llén Book 2014 Springer International Publishing Switzerland 2014 Birth defect.Con

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Historical background related to ,,eight while overweight was combined with a decreased risk. Unwanted childlessness was associated with an increased risk for small head circumference. No drug use was associated with a clinical diagnosis of microcephaly, but maternal use of anticonvulsants or neuroleptics resulted in an increased risk for a small head circumference.

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ONYM

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Implications for Policy and Research,n with maternal drug use was seen: aminosalicylic acid drugs, antihypertensives, ovarian stimulation, thyroid hormone, antibiotics, anticonvulsants, and antiasthmatics. In analyses of specific cardiovascular groups, further associations were found: immunosuppressives, antidepressants (especially tricyclics and paroxetine) and septal defects.

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Cardiovascular Defects,n with maternal drug use was seen: aminosalicylic acid drugs, antihypertensives, ovarian stimulation, thyroid hormone, antibiotics, anticonvulsants, and antiasthmatics. In analyses of specific cardiovascular groups, further associations were found: immunosuppressives, antidepressants (especially tricyclics and paroxetine) and septal defects.

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Zhifeng Ren,Yucheng Lan,Yang Wang, and neuroleptics (close to statistically significant). Use of antihistamines was associated with a ”protective” effect, notably after meclozine which is a standard drug for treatment of nausea and vomiting in pregnancy.

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A Short History of Birth Defect Epidemiology,defect registers around the world, started in order to detect a new thalidomide-like drug as quickly as possible. An international organization was formed in 1974, trying to coordinate data from the different registers and other international or national organizations exist.

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