Titlebook: Enzyme Kinetics in Drug Metabolism; Fundamentals and App Swati Nagar,Upendra A. Argikar,Donald J. Tweedie Book 2014 Springer Science+Busine

bromide

Enzyme Kinetics, Inhibition, and Regioselectivity of Aldehyde Oxidased in the clinic because the clearance or toxicity is underestimated by preclinical species. Human AO is much more active than rodent AO, and dogs do not have functional AO. While AOs normally make non-reactive metabolites such as lactams, the metabolic products often have much lower solubility that