Titlebook: Endocrine Disrupters; Environmental Health Polyxeni Nicolopoulou-Stamati (ASPIS Project Co-or Book 2001 Springer Science+Business Media B.V

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Mechanisms Underlying Endocrine Disruption and Breast Canceroncogenes; disturbances in signal transduction pathways and interference with several accessory mechanisms of carcinogenesis. The particular carcinogenesis mechanisms underlying the action of (xeno)oestrogens are discussed. This mechanism implicates the absence of any threshold and-consequently-indu

heterodox

Human Exposure to Endocrine Disrupting Chemicals: The Case of Bisphenols exposure or potential consequential health risks. It can be affirmed that: i) ‘bisphenols’ is a broad term that includes various compounds that are structurally similar to bisphenol-A and are widely used in the chemical industry; ii) human exposure to bisphenols is a significant, demonstrated and i

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Risk Assessment of Endocrine Disruptersantify the health consequences of ED exposure in a reliable way. Fundamental information is currently lacking for each of the steps of the risk assessment paradigm. The most important knowledge gaps concern: the availability of a validated set of EDs tests, knowledge on the mechanisms through which

Oration

Endocrine Disrupting Chemicals: A Conceptual FrameworkA major consequence of this is the virtual absence of the phenomenon of ‘bioaccumulation’ of natural compounds. We then consider the reasons why some anthropogenic synthetic chemicals bioaccumulate, and discuss the consequences for the functioning of the endocrine system and consequences for the eff

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Pesticide Authorisation: Existing Policy with Regard to Endocrine Disruptersof adverse effects that result from endocrine disruption. Additional end-points can be included in the existing studies to improve their performance. Alternative studies and techniques (. and/or .) can help to further characterise the effects that may be observed, and these techniques could be inclu

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Endocrine Disruption — The Industry Perspectiveesearch:.By supporting this programme, the intention of the European Chemical Industry is to contribute to the consolidation of the existing knowledge and the establishment of a solid scientific framework to assist decision-makers. The results will be published in peerreviewed journals and the infor

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Assessment of the Impact of Endocrine Disrupters on Human Health and Wildlife: Activities of the Worrategy. In 1997, the Intergovernmental Forum on Chemical Safety underlined the need to address the issue of endocrine disrupters on a broad international level, to co-ordinate testing and assessment strategies, and to develop an international inventory of research activities. The World Health Organi