Titlebook: Emerging Concepts of Tumor Exosome–Mediated Cell-Cell Communication; Huang-Ge Zhang Book 2013 Springer Science+Business Media New York 201

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https://doi.org/10.1007/978-1-4419-6460-1 outward budding of portions of the plasma membrane, membrane vesicles of 30–100?nm, called exosomes are secreted during fusion of endosomal multivesicular bodies with the cell surface. Exosomes contain membrane and cytosolic components that include proteins, lipids and RNAs. Exosomes from different

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monogamy

https://doi.org/10.1007/978-3-7091-3790-1rane and cytoplasmic proteins, mRNA, and microRNA into target cells. Due to this shipping of information, exosomes are considered to be a most promising therapeutic tool for multiple diseases..Whereas knowledge on the composition of exosomes is rapidly increasing, the mode of selective recruitment i

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Palpable

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https://doi.org/10.1007/978-3-322-94509-9communication occurs through direct interaction, secreted factors as well as microvesicles carrying proteins and nucleic acids. The tumor microvesicles carry a wide range of cargo, including oncogenic proteins, fragmented DNA, mRNA and non-coding RNA with regulatory functions that can be horizontall

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https://doi.org/10.1057/9780230501744been focused on the role of exosomes in malignant progression and metastasis. This chapter highlights the functional roles of tumor exosomes in influencing pre-metastatic niche formation and metastatic behavior. We discuss their interaction with cells within the tumor microenvironment (bone marrow-,