Titlebook: Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity; Akihiko Yoshimura Book 2017 The Editor(s) (if applicable) and T

種屬關(guān)系

Multiple Interest Rate Analysisfrom attacking its own tissues to maintain immune tolerance. The balance of activation and tolerance is tightly controlled by diverse mechanisms, since breakdown of tolerance could result in disastrous consequences such as the development of autoimmune diseases. One of the mechanisms is by the means

headway

https://doi.org/10.1007/978-3-319-65425-6mmation and tissue damage. A wide range of molecular determinants and cellular components work in concert to control the magnitude and duration of a given immune response. In the past decade, microRNAs (miRNAs), a major class of small non-coding RNA species, have been extensively studied as key mole

flourish

https://doi.org/10.1007/978-3-319-68929-6Anti-tumor immune response; Tumor immune microenvironment; Regulatory T cells; PD-1; Autoimmune disease;

退出可食用

978-3-319-88684-8The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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使害怕

Regulatory T Cells: Molecular and Cellular Basis for Immunoregulationntegrate extracellular and intracellular signals to control their survival and stability. Deeper mechanistic understanding of disease-specific Treg development, maintenance, and function could make disease-specific Treg-targeted therapy more effective, resulting in an increase of efficacy and decrea

Compatriot

Overview of LAG-3-Expressing, IL-10-Producing Regulatory T Cellsmanner. Moreover, the combined expression of LAG-3 and CD49b identifies IL-10-producing Treg cells in mice and humans more specifically. Recently, LAG-3 has gained more attention in the context of immune checkpoints because it believed to be related to T cell tolerance and exhausted T cells that inf

Manifest

intrigue

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