Titlebook: Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4; Kenneth V. Honn,Lawrence J. Marnett,Edward A. Den

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Investigation of a Second 15,-Lipoxygenase in Humans and its Expression in Epithelial Tissuesren, 1975). At nearly the same time, Rapoport and colleagues recognized the existence of the 15.-lipoxygenase in reticulocytes (Schewe et al., 1975), and discovery of the leukocyte 5.-lipoxygenase was reported in the following year (Borgeat et al., 1976). Subsequent metabolism studies and molecular

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Comparison of Prostaglandin H Synthase-1 and -2 Structural Stabilitiesation and inflammation.. Both isoforms have two catalytic activities: oxygenation of arachidonate to form PGG. (cyclooxygenase), and reduction of PGG. to form PGH. (peroxidase). The overall amino acid identity between the human PGHS isoforms is about 60%, with much higher conservation in residues re

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978-1-4613-7171-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

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Developing University Social ResponsibilityLipoxygenases (LOXs) are enzymes which oxygenate polyenoic fatty acids containing 1,4-pentadiene structures to their corresponding hydroperoxy derivatives (Yamamoto, 1992). They are distributed over the whole animal and plant kingdoms.

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