Titlebook: Effects of Nicotine on Biological Systems II; Paul Brian Sydenham Clarke,Maryka Quik,Klaus Thura Book 1995 Springer Science+Business Media

價值在貶值

Conjuction

Neuronal Nicotinic Receptor Structure and Functionit stoichiometry (α4).(β2). and accounts for >90% of the high affinity nicotine binding in mammalian brains. Chronic treatment of cells transfected with α4β2 AChRs causes an increase in the amount of AChR with pharmacological characteristics and a time course that parallel the nicotine-induced incre

Certainty

Determinants Regulating Neuronal Nicotinic Receptor Functionceptor as a model of the superfamily of allosteric proteins. Chimera between the neuronal nicotinic acetylcholine receptor (nAChR) and the serotoninergic (5HT.) receptor revealed functional protein domains, and also allowed the demonstration of the allosteric modulation induced by extracellular calc