Titlebook: Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis; Otto R. Hommes,Giancarlo Comi Book 2004 Springer-Verlag Italia 20

GRILL

tting (RR) to the progressive stages. It is becoming increasingly clear that progressive multiple sclerosis (MS) is associated with axonal loss and that axonal damage occurs early during RRMS. Disease progression thus develops well in advance of clinical progression and remains subclinical because,

Anonymous

time. However, conventional MRI is not able to characterize and quantify the tissue damage within and outside these lesions. Other quantitative MR techniques have the potential to overcome such limitation. Among these techniques, MR spectroscopy (MRS), magnetization transfer imaging (MTI), and diffu

植物群

https://doi.org/10.1007/978-981-97-7827-0lished of these classifications is age-associated memory impairment (AAMI) [1], but it is generally non-progressive and is thus more likely to be a phenomenon of normal aging [2, 3]. The terms “age-related cognitive decline” (ARCD) and “aging-associated cognitive decline” have been proposed recently

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苦惱

Conflagration

Obstruction

he more non-specific T2-hyperintense lesions, which show greater signal intensity than normal brain on T2-weighted magnetic resonance imaging (MRI). The T1-hypointense lesions are areas of axonal loss, as well as matrix disruption [1, 2]. T1-hypointense lesions are moderately correlated with focal r

DRAFT

uantified by a number of common, easily available, neuro-ophthalmological techniques. Detection of an early, subtle, optic neuropathy is relatively easy compared with many of the difficult-to-document sensory or even motor complaints in early multiple sclerosis (MS).