Titlebook: Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives; Mohammed Tarique Book 2024 The Editor(s) (if applicable) and The

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Onyeka Obioha,Candrice Heath,Pearl E. Grimestimalarial drugs, efficiencies, and challenges. Many parasites depend on kinases for various physiological activities, and these enzymes are easily targeted with drugs provided. By virtue of strong conserved nature of all binding sites from ATP molecules, it is difficult to find Plasmodium kinase in

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different classes of proteasome inhibitors developed including β-lactones, peptide aldehydes, α′β′ epoxyketone, asparagine ethylene diamines, peptide sulphonyl fluorides, peptide boronates, and cyclic peptides. This chapter also highlights how the proteasome inhibitors are validated through in vitr

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acuole, hemoglobin is destroyed progressively by a variety of proteases such as aspartic proteases, cysteine proteases, metalloproteases, and aminopeptidases. As a result, the parasite uses hemoglobin as a supply of amino acids. In this chapter, we will go over the vital role of the food vacuole and

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Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives

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Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives978-981-19-4484-0

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