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Titlebook: Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives; Mohammed Tarique Book 2024 The Editor(s) (if applicable) and The

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發(fā)表于 2025-3-21 17:14:08 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives
編輯Mohammed Tarique
視頻videohttp://file.papertrans.cn/285/284834/284834.mp4
概述Reviews novel molecular targets for antimalarial drug development.Explores metabolic enzymes as druggable targets against malaria.Examines Plasmodium Kinases as potential drug targets for malaria
圖書封面Titlebook: Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives;  Mohammed Tarique Book 2024 The Editor(s) (if applicable) and The
描述.This book offers a comprehensive exploration of malaria, a life-threatening disease affecting millions globally, with a focus on the parasitic organisms of the genus Plasmodium that cause it. It discusses the challenges posed by the disease, especially in economically developing regions, and delves into the biology and pathophysiology of the Plasmodium species, including their genetic flexibility and resistance to treatments. Special attention is given to P. falciparum, the most dangerous of these parasites, detailing its complex life cycle, interaction with human hosts, and the severe clinical manifestations it can induce. The book further explores the global health concern of antimalarial drug resistance, highlighting the WHO‘s efforts in combating the disease and the necessity for novel treatments. Innovative research directions, such as targeting the unique organelles of Plasmodium like the apicoplast and employing proteasome inhibitors, are thoroughly examined as potential strategies in the development of new antimalarial drugs. Additionally, it addresses the critical role of the hemoglobin digestion process in the parasite‘s lifecycle, presenting it as a promising target for
出版日期Book 2024
關(guān)鍵詞Malaria; Plasmodium falciparum; Drug targets; Protein kinases; Tranporter inhibitors
版次1
doihttps://doi.org/10.1007/978-981-19-4484-0
isbn_softcover978-981-19-4486-4
isbn_ebook978-981-19-4484-0
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-21 20:44:58 | 只看該作者
Book 2024sms of the genus Plasmodium that cause it. It discusses the challenges posed by the disease, especially in economically developing regions, and delves into the biology and pathophysiology of the Plasmodium species, including their genetic flexibility and resistance to treatments. Special attention i
板凳
發(fā)表于 2025-3-22 02:18:44 | 只看該作者
地板
發(fā)表于 2025-3-22 06:57:45 | 只看該作者
Pathogenesis of ,ical reactions, and numerous clinical manifestations of variable severity and symptoms. Female Anopheles mosquito bites a person and delivers the parasite into the blood. Normally, the children under 5 and pregnant women are at most danger from malaria claiming the death toll up to 2.5 million peopl
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發(fā)表于 2025-3-22 11:10:47 | 只看該作者
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發(fā)表于 2025-3-22 12:52:59 | 只看該作者
Metabolic Pathways of Enzymes: Therapeutic Targets and Prospects for Innovative Antimalarial Drugs,ate. The present standard of care depends on various antimalarial drugs and preparations and one of the most important is artemisinin combination therapy (ACT) aimed at to reduce Plasmodium count in body. The ACT treatment is very helpful in only few specific regions and had shown weakest performanc
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發(fā)表于 2025-3-22 19:52:15 | 只看該作者
Targeting Apicoplasts in ,, Origin and Pathways,logical target that is strengthen by the virtue of its peculiar shared prokaryotic and plant-like cellular properties, functions, and diverse activities, which has made the apicoplast as one of the interesting focuses for future research in pharmacology. Research into the apicoplast has uncovered in
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發(fā)表于 2025-3-23 03:02:10 | 只看該作者
: Transporter and Drug Target, the globe. In spite of persistent efforts by a large number of countries and substantial investments, the eradication of malaria has proven to be difficult. This is primarily due to the emergence of multidrug resistance against a variety of conventional medications, including artemisinin, which is
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發(fā)表于 2025-3-23 06:55:35 | 只看該作者
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