Titlebook: Drug Repurposing; Innovative Approache Naveen Chella,Om Prakash Ranjan,Amit Alexander Book 2024 The Editor(s) (if applicable) and The Autho

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https://doi.org/10.1007/978-3-642-81306-1cessful and old examples of drug repurposing mentioned in literature include sildenafil, aspirin, and zidovudine. The approval by the Food and Drug Administration (FDA) for the use of several repurposed drugs for COVID-19 treatment on an emergency basis has brought attention to the practice of drug

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Diane R. Dowd,Paul N. MacDonaldhapter covers drug regulatory and intellectual property rights (IPR) related aspects of drug repurposing. The goal is to help practitioners understand regulatory issues for drugs or product modifications and the repositioning of existing substances. The regulatory background and examples of drug mod

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Methodologies Adopted in Drug Repurposing, anecdotes, and other relevant human data is a crucial step. In this process, Artificial Intelligence (AI), bioinformatics, genetic data, clinical analysis, molecular docking, pathways, signatures, targets, phenotypes, and binding tests can help understand drug–protein interactions. The current chap

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Drug Repurposing in Cancer Therapy, have shown positive results. Even some anticancer agents confirmed their potential effects in other cancers. Here, data mining approaches have been found rationale to provide strength in the repurposing pipeline. Especially if dose compatibility of the repurposed candidate is found for anticancer t

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Drug Repurposing in Inflammatory Disorders,ge or infection and is involved in the pathophysiology of almost all diseases. But inflammation can turn into the dark side of the sword when it affects healthy tissues or extends to the body as a whole for a long time, referred to as chronic inflammation. Even though there are various treatments fo

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Drug Repurposing in CNS Disorders, computational approaches. In addition, a few case studies involving drug repurposing for specific CNS disorders, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Amyotrophic lateral sclerosis, Spinal muscular atrophy, and Epilepsy are presented in this chapter.

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Clinical Trials on Repurposed Drugs: An Overview,cessful and old examples of drug repurposing mentioned in literature include sildenafil, aspirin, and zidovudine. The approval by the Food and Drug Administration (FDA) for the use of several repurposed drugs for COVID-19 treatment on an emergency basis has brought attention to the practice of drug