Titlebook: Dynamics of Brain Edema; Proceedings of the 3 Hanna M. Pappius (Associate Professor, Associate N Conference proceedings 1976 Springer-Verla

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The Starling Hypothesis of Capillary Fluid Exchange in Relation to Brain Edema and in some instances even exceeds, plasma COP, thereby upsetting the balance of transcapillary fluid exchange in favor of retention of edema fluid in brain tissue. The findings also suggest that plasma COP and the systemic factors affecting it are important in the dynamics of the protein exudation

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Production, Circulation and Absorption of Brain Interstitial Fluidng perivascular spaces and between fiber tracts. However, we disagree with the conclusion that all ISF drains into the subarachnoid space and suggest, instead, that some fluid may be absorbed in the brain, particularly across fenestrated blood vessels.

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Water Content of Rat Brain in Acute Arterial Hypertensionby hypercapnia aggravates this permeability disturbance. The water content in acute hypertension of 30 min duration was increased in hypercapnic but not in normo- or hypocapnic rats. The effect of hypercapnia per se on the blood-brain barrier is discussed in view of recent experimental findings.

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The Blood-Brain Barrier in Experimental Seizures, (2) seizure-induced hypertension causes most of the barrier breakdown and enhanced micropinocytosis, and (3) under these conditions there is no evidence of cerebral edema in the areas of obvious BBB breakdown.

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