Titlebook: Drugs of Abuse, Immunomodulation, and Aids; Herman Friedman,John J. Madden,Thomas W. Klein Book 1998 The Editor(s) (if applicable) and The

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Opiate Effects on , Human Retroviral Infection, includes the use of certain injected pharmaceuticals. Some investigations have suggested that HIV-1 infected individuals who are injecting drug users (IDUs) may undergo an accelerated rate of progression to AIDS. It is known that opioid receptors exist on cells pertinent to immune function, and tha

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FIV,clear. There is a pressing need for appropriate animal models to examine the role of opiates on lentivirus disease progression, particularly the CNS form of the disease. The FIV/cat model has now been developed as a legitimate system for the study of lentivirus induced neurologic disease. Not only d

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Changes in Kappa Opioid Receptor Expression During Maturation of Mouse Lymphocytes,rs. and neuropeptides,. which are common to both systems. In particular, of the neuropeptides, the opioid peptides have been shown to exert profound modulating effects on various immune cell functions.. In addition, detection of messenger RNA encoding for μ,. δ,. and k. opioid receptors in lymphocyt

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Morphine During Pregnancy in the Rat,e mechanism leading to these long-term effects is not clear, but numerous studies have documented both physiological and behavioral changes in adulthood resulting from such perinatal exposure (1-4). Although the nervous system shows numerous long term effects, it is probably not the only organ syste

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,Morphine’s Immunologic and Analgesic Effects,mmune deficiency syndrome remains a prominent medical problem, this use of the opioids has led to concern regarding their effects on the normal functioning of the immune system. In fact, studies investigating the immunomodulatory effects of morphine have begun to reveal the pervasive nature of these

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Immunomodulation Mediated by Microinjection of Morphine into the Periaqueductal Gray Matter of the cell activity, and T and B lymphocyte functions are altered following administration of opioid agonists. There is growing evidence suggesting that there exists a complex, bidirectional link between central nervous system (CNS) and immune system.. Elucidation of the mechanism(s) through which central

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